Tsuyoshi Hirashima

Graduate School of Medicine, Kyoto UniversityLecturer*Profile is at the time of the award.

2019Inamori Research GrantsBiology & Life sciences

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Research topics: Mathematical Modeling for Mechano-chemical Feedback System in Multicellular Tissues

Keyword

Summary: Cells receive and generate power for themselves through intracellular signal transduction. Since they constantly receive and generate power, when populations of cells are concentrated, adjacent cells begin to push and pull each other, thus creating a complicated temporal-spatial pattern (in the form of vibrations or waves) with power and intercellular signal activation. To understand the mechanism through which a complicated temporal-spatial pattern is formed, analysis and simulation of a mathematical model based on experimentally obtained data are effective. In this proposed research, mathematical modeling of a dynamics-biochemical feedback system in a cell population will be performed based on experimentally obtained quantitative data in order to understand the mechanism of forming a complicated temporal-spatial pattern.

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I will immerse myself in academic research to seek greater originality in my undertakings.

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