Hirohisa Ohno

Assistant Professor , Center for iPS Cell Research and Application, Kyoto University*Profile is at the time of the award.

2024Inamori Research GrantsBiology & Life sciences

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Research topics: Development of artificial RNA enabling precise gene expression control

Keyword

Summary: In recent years, artificial messenger RNA (mRNA), exemplified by RNA vaccines, has garnered significant attention. RNA, in principle, poses no risk of integration into the genome and offers advantages such as ease of design modification and synthesis tailored to target genes. However, improvements in stability and specificity are desired.
This study aims to enhance specificity and achieve high safety and efficacy by endowing RNA itself with the ability to identify target cells and express genes only in those cells, thereby developing artificial mRNA with improved specificity.

Message

I am deeply honored to have been awarded this research grant. I am determined to conduct engaging fundamental research that can also contribute to society. I look forward to striving towards this goal.

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