Hiroshi Inaba

Graduate School of Engineering, Tottori UniversityAssistant Professor*Profile is at the time of the award.

2019Inamori Research GrantsScience & Engineering

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Research topics: Encapsulation of exogenous proteins inside microtubules based on the peptide design toward elucidation of physical property of the protein-encapsulated microtubules

Keyword

Summary: In our body, there are tubular structures called as "microtubules". Microtubules, which consists of tubulin proteins, change their stability and structures precisely to maintain the cellular functions. How do they modulate these properties? Recently, it is estimated that the unknown particles bind to the inside of microtubules to stabilize microtubules. However, the details remain unknown.
Recently, we have developed a peptide which binds to the inside of microtubules. In this research, by conjugating the peptide to proteins, we aim to encapsulate various proteins inside microtubules and analyze the effects on microtubules. This research will show new methodology to elucidate the functions of microtubules in nature.

Message from recipient

It is a great honor for me to take the Inamori research grant, especially toward the basic research concept. Through the research, I would like to show a new approach to elucidate the functions of microtubules.

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