Jumpei Taguchi

Project Assistant Professor, The Institute of Medical Science, The University of Tokyo*Profile is at the time of the award.

2024Inamori Research GrantsBiology & Life sciences

researchmap

Research topics: BAC-based humanization with CRISPR-Cas9 ribonucleoprotein in mouse embryonic stem cells

Keyword

Summary: Mice have a genome that is 99% similar to humans and are useful model animals for diverse range of medical and life science researches. On the other hands, since there are some aspects that differ from humans, such as control mechanisms of gene expression and three-dimensional structure of proteins, it has been pointed out that there is a need for genomic humanization technology to replace target mouse gene locus with human gene locus. However, genomic humanization requires inducing recombination of a wide range of genomic regions, and versatile genomic humanization technology has not been established. In this research, we aim to develop full-length genomic humanization technology targeting genomic regions over 100kb by focusing on ES cells that has high homologous recombination efficiency.

Message

I'm great honored to receive generous support for my research as Inamori Research Grants. I would like to develop a versatile genomic humanization technology and contribute to advancement of medical and life science research.

Find other recipients

Biology & Life sciences

Hiroshi Miyanishi

University of Miyazaki

Jun-ichi Sakamaki

Juntendo University

Shunsuke Tagami

RIKEN

Kazutoshi Iijima

Yokohama National University

Noriyoshi Usui

Osaka University

Daisuke Takimoto

Material Science

Kazutoshi Kasho

Biology & Life sciences Life Science

Ryusuke Hatae

Kyushu University

Akiko Kanehara

Ayuko Hoshino

The University of Tokyo

InaRIS Fellow

Yuki Honda

Material Science

Masaru Hojo

Kwansei Gakuin University

Yuma Takahashi

Nara Institute of Science and Technology

Akari Fujimoto

Masayuki Tera

Tokyo University of Agriculture and Technology

Kiyoharu Fukushima

Kyoto University

Daisuke Ono

Biology & Life sciences Life Science

Koichi Murata

Kyoto University

Saori Morino-Koga

The University of Tokyo

Yu Fukasawa

Tohoku University

Yuka Iwasaki

RIKEN

Kenta Maruyama

Aichi Medical University

Yuhei Chadani

Okayama University

Yoshifumi Yamaguchi

Hokkaido University

InaRIS Fellow

Atsushi Fujimura

Okayama University

Takeshi Kawabe

Biology & Life sciences Medicine

Yukiko Kimura

National Institutes of Natural Sciences

Masaki Uchida

Satoshi Minami

Osaka University

Azusa Kondoh

Pharmacy Biology & Life sciences

Ritsuko Morita

Biology & Life sciences Life Science

Nobuhiko Yokoshi

Keio University

Hironori Takeda

Hiroshima University

Nami Minato

Yoshiaki Abe

University of Tsukuba

Hirofumi Toda

University of Tsukuba

Dana Ulanova

Kochi University

So Nagaoka

Biology & Life sciences Life Science

Takaaki Ozawa

Osaka University

Shun Shibata

Tohoku University

Misuzu Hashimoto

Gifu University

Taichi Itoh

Biology & Life sciences

Tomonori Nakamura

Kyoto University

Tsuyoshi Terakawa

Kyoto University

Toyoaki Natsume

Research Organization of Information and Systems

Katsuyoshi Takaoka

Minako Ito

Hiroshi Suzuki

Nagoya University

InaRIS Fellow

Shintaro Yamaguchi

Hiroshi Masai

Material Science

Kenichi Watanabe

Kaori Sako

Yukiko Kamiya

Hidefumi Shinohara

Nagoya University

Tomohisa Hosokawa

Nagoya University

Tetsuya Kadonosono

Tokyo Institute of Technology

Kenta Hirami

Hiroshi Nishimasu

The University of Tokyo

InaRIS Fellow

Taro Fuchikawa

Osaka City University

Takashi Iwasaki

Tottori University

Masahiro Morimoto

Yusaku Iwasaki

Kazunori Kume

Masakazu Hirota

Satoshi Miura

Information Science

Shintaro Munemasa

Okayama University

Aiko Sada

Okayama University

Miu Tamamitsu

The University of Tokyo

Tomohiro Otsuka

Masato Yamamichi

Research Organization of Information and Systems

Takumi Ogawa

Osaka Prefecture University

Miyako Shiraishi

Osaka University

Yuto Takenaka

Ritsumeikan University

Satoshi Iwakami

Kyoto University

Yoshiyuki Manabe

Tokai University

Hideaki Morishita

Biology & Life sciences Life Science

Susumu Jitsuki

Biology & Life sciences Life Science

Kazuhiko Yamamuro

Takashi Fukaya

The University of Tokyo

Katsuma Hayashi

Kyoto University

Junichi Kikuta

University of Tsukuba

Yuji Sakai

Tokushima University

Taichi Noda

The University of Tokyo

Keita Takahashi

Masafumi Kodama

Biology & Life sciences

Akihiro Funamizu

Information Science

Tomomi Koshiyama

Ritsumeikan University

Yosuke Togashi

Biology & Life sciences Medicine

Yuichiro Mishima

Kyoto Sangyo University

Hirohisa Ohno

Kyoto University

Seiya Takayanagi

Yuta Hiraike

The University of Tokyo

Akihiro Nishiguchi

National Institute for Materials Science

Kenji Ikeda

Tokyo Medical and Dental University

Hiroshi Nomoto

Masashi Kanayama

Tokyo Medical and Dental University

Kenji Osabe

Tokyo Institute of Technology

Takanori Wakatake

Nara Institute of Science and Technology

Masashi Mamada

Material Science

Shizue Ohsawa

Nagoya University

Tomomi Wakabayashi

Osaka University

Masayuki Tsukasaki

The University of Tokyo

Akiko Ogawa

Biology & Life sciences Life Science

Yasuo Oguri

Biology & Life sciences Life Science

Keiichiro Suzuki

Osaka University

Hitoshi Miyakawa

Utsunomiya University

Daisuke Ino

Osaka University

Toshiyuki Kowada

Biology & Life sciences Life Science

Tomoya Yamaguchi

Kumamoto University

Tomoyuki Furuta

Okayama University

Chie Aoki-Utsubo

Kobe University

Takayuki Suzuki

Nagoya University

Takashi Tsuchimatsu

Chiba University

Miharu Maeda

Biology & Life sciences Life Science

Masayuki Morita

Ehime University

Yoshihiro Sakita

Makoto Kobayashi

Tsuyoshi Hirashima

Kyoto University

Hidenori Nishio

Nagoya City University

Toshiki Sawada

Material Science

Shu Nakao

Ritsumeikan University

Akihiko Mougi

Shimane University

Takayuki Kuraishi

Kanazawa University

Kuniyasu Saitoh

Asano Ishikawa

Research Organization of Information and Systems

Tomoko Okamoto

Gosuke Hayashi

Pharmacy Biology & Life sciences

Toshiro Moroishi

Koji Atarashi

Shohei Nosaki

University of Tsukuba

Kenichi Kimura

University of Tokyo

Hisaaki Hirose

Osaka University

Rie Wakabayashi

Kyushu University

Takahiro Masuda

Yusuke Kobayashi

Takashi Tanaka

Kazuya Matsuo

Hidenori Okamura

Tohoku University

Tsuyoshi Waku

Doshisha University

Shohei Yamamoto

Tokyo Medical and Dental University

Michihito Kono

Akihiro Goto

Biology & Life sciences Life Science

Kunio Kondoh

Mizuki Endo

Takuma Kokusho

Mitsuaki Kashiwagi

Biology & Life sciences Life Science

Wakana Tanaka

The University of Tokyo

Yusuke Kimata

Biology & Life sciences Life Science

Teruhiko Imamura

Shunsuke Kon

Tokyo University of Science

Ayaka Ito

Seiji Takashima

Shinshu University

Ryo Fujimoto

Kobe University

Chikara Abe

Gifu University

Takashi Shimada

Biology & Life sciences

Takumi Suzuki

Ibaraki University

Tomonori Matsumoto

Biology & Life sciences Medicine

Yoshihiro Ujihara

Nagoya Institute of Technology

Takuya Matsumoto

Osaka Prefecture University

Atsushi Anzai

Biology & Life sciences Medicine

Nobuharu Suzuki

Tokyo Medical and Dental University

Kunihiko Morihiro

The University of Tokyo

Chihiro Maeda

Material Science

Masanori Nomoto

University of Toyama

Mitsuru Tsuge

Okayama University

Masahiko Saito

Material Science

Hideaki Kato

The University of Tokyo

Kyoko Miura

Kumamoto University

Tomomi Tsunematsu

Hokkaido University

Hidehisa Kawashima

University of Tsukuba

June-Sik Kim

RIKEN

Kyogo Kobayashi

Kyushu University

Masayuki Sakamoto

Kumamoto University

Atsushi Saito

Sapporo Medical University

Ayako Gotoh

Konan University

Mizuki Watanabe

Hokkaido University

Kazuki Ide

Kozue Shiomi

Biology & Life sciences

Yohei Hayashi

Tohoku University

Takuya Motooka

Hiroyoshi Y. Tanaka

Okayama University

Kotaro Mizuta

Kyoto University