Masanori Nomoto

Associate Professor, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama*Profile is at the time of the award.

2024Inamori Research GrantsBiology & Life sciences

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Research topics: Deciphering the information processing rule in the sleeping brain

Keyword

Summary: As in dreaming, the brain is active not only during wakefulness, but also during sleep. Brain activity during sleep is necessary for memory consolidation and various cognitive functions. However, the mechanism of how the brain processes information on cognitive functions during sleep remains unclear. In this study, we focus on the olfactory pathway, which is not easily affected during sleep, and use an optogenetic pseudo-olfactory stimulation to seamlessly track brain representations and memory information related to smells during wakefulness and sleep. Results of this research will elucidate the dynamics and principle of brain information processing during wakefulness and sleep states.

Message

I appreciate the grant support for our research.
The aim is to seamlessly record and analyze the input-output responses during wakefulness and sleep, clarifying the relationship between the brain's information processing modes and cognitive functions across wakeful and sleeping states.
The ultimate goal is to find a systematic correlation—a sleep-wake Rosetta Stone—thereby decoding information processing during sleep.

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