Akiko Ogawa

Assistant Professor, Institute of Development, Aging and Cancer, Tohoku University *Profile is at the time of the award.

2022Inamori Research GrantsBiology & Life sciences

researchmap

Research topics: Regulatory roles of modified RNA metabolism in immunity and disease

Keyword

Summary: Cellular RNA species contain a wide variety of post-transcriptional chemical modifications. About 150 species of RNA modifications have been identified in RNA species from all kingdoms of life. During RNA catabolism, most modified nucleosides are resistant to degradation and are released into the extracellular space. N6-methyladenosine (m6A), widely recognized as an epigenetic mark in RNA, specifically activates human GPCR and acts as a signaling molecule and triggers pathophysiological immune responses, a previously unreported property of RNA modifications. However, the metabolism of m6A which will terminate the m6A-mediated signaling has been unknown. The goal of this research project is to elucidate the regulatory pathway of m6A metabolism.

Message

I would like to pioneer a new nucleic acid physiology from the viewpoint of metabolism of RNA modifications, and through my research, I would like to aim for a radical cure of diseases for which there has been no cure so far.

Find other recipients

Biology & Life sciences

Kazunori Kume

Tomoyuki Furuta

Okayama University

Yuta Hiraike

The University of Tokyo

Yukiko Kamiya

Shizue Ohsawa

Nagoya University

Yuhei Chadani

Okayama University

Takahiro Masuda

Masayuki Tsukasaki

The University of Tokyo

Kunihiko Morihiro

The University of Tokyo

Takaaki Ozawa

Osaka University

Daisuke Takimoto

Material Science

Mitsuru Tsuge

Okayama University

Seiya Takayanagi

Hidefumi Shinohara

Nagoya University

Takuya Matsumoto

Osaka Prefecture University

Chikara Abe

Gifu University

Yuka Iwasaki

RIKEN

Tomomi Wakabayashi

Osaka University

Masato Yamamichi

Research Organization of Information and Systems

Toyoaki Natsume

Research Organization of Information and Systems

Nobuharu Suzuki

Tokyo Medical and Dental University

Kenji Ikeda

Tokyo Medical and Dental University

Hiroshi Nishimasu

The University of Tokyo

InaRIS Fellow

Shun Shibata

Tohoku University

Makoto Kobayashi

Atsushi Saito

Sapporo Medical University

Yusuke Kimata

Biology & Life sciences Life Science

Masayuki Sakamoto

Kumamoto University

Tomohiro Otsuka

Masahiko Saito

Material Science

Takashi Tanaka

Hisaaki Hirose

Osaka University

Tomomi Tsunematsu

Hokkaido University

Masashi Mamada

Material Science

Takashi Iwasaki

Tottori University

Dana Ulanova

Kochi University

Minako Ito

Tsuyoshi Hirashima

Kyoto University

Yusaku Iwasaki

Takashi Tsuchimatsu

Chiba University

Tomoya Yamaguchi

Kumamoto University

So Nagaoka

Biology & Life sciences Life Science

Hidehisa Kawashima

University of Tsukuba

Kyoko Miura

Kumamoto University

Takayuki Suzuki

Nagoya University

Kiyoharu Fukushima

Kyoto University

Ritsuko Morita

Biology & Life sciences Life Science

Yoshifumi Yamaguchi

Hokkaido University

InaRIS Fellow

Toshiyuki Kowada

Biology & Life sciences Life Science

Yuma Takahashi

Nara Institute of Science and Technology

Tomonori Nakamura

Kyoto University

Yusuke Kobayashi

Kenta Hirami

Hidenori Okamura

Tohoku University

Katsuma Hayashi

Kyoto University

Masayuki Tera

Tokyo University of Agriculture and Technology

Kazutoshi Kasho

Biology & Life sciences Life Science

Hideaki Kato

The University of Tokyo

Junichi Kikuta

University of Tsukuba

Kenta Maruyama

Aichi Medical University

Miharu Maeda

Biology & Life sciences Life Science

Takashi Shimada

Biology & Life sciences

Misuzu Hashimoto

Gifu University

Jun-ichi Sakamaki

Juntendo University

Noriyoshi Usui

Osaka University

Nobuhiko Yokoshi

Keio University

Hirofumi Toda

University of Tsukuba

Koichi Murata

Kyoto University

Teruhiko Imamura

Takumi Suzuki

Ibaraki University

Shunsuke Kon

Tokyo University of Science

Shohei Yamamoto

Tokyo Medical and Dental University

Yu Fukasawa

Tohoku University

Toshiki Sawada

Material Science

Yuto Takenaka

Ritsumeikan University

Takanori Wakatake

Nara Institute of Science and Technology

Satoshi Minami

Osaka University

Tomohisa Hosokawa

Nagoya University

Asano Ishikawa

Research Organization of Information and Systems

Miyako Shiraishi

Osaka University

Yoshihiro Sakita

Masanori Nomoto

University of Toyama

Keita Takahashi

Gosuke Hayashi

Pharmacy Biology & Life sciences

Yohei Hayashi

Tohoku University

Daisuke Ono

Biology & Life sciences Life Science

Takumi Ogawa

Osaka Prefecture University

Hiroshi Suzuki

Nagoya University

InaRIS Fellow

Hironori Takeda

Hiroshima University

Ryo Fujimoto

Kobe University

Hideaki Morishita

Biology & Life sciences Life Science

Kyogo Kobayashi

Kyushu University

Shu Nakao

Ritsumeikan University

Saori Morino-Koga

The University of Tokyo

Kazuhiko Yamamuro

Hiroshi Masai

Material Science

Kazutoshi Iijima

Yokohama National University

Daisuke Ino

Osaka University

Hiroshi Nomoto

Ayuko Hoshino

The University of Tokyo

InaRIS Fellow

Tsuyoshi Waku

Doshisha University

Shunsuke Tagami

RIKEN

Atsushi Anzai

Biology & Life sciences Medicine

Mitsuaki Kashiwagi

Biology & Life sciences Life Science

Rie Wakabayashi

Kyushu University

Akihiro Funamizu

Information Science

Masaru Hojo

Kwansei Gakuin University

Yoshiyuki Manabe

Tokai University

Satoshi Iwakami

Kyoto University

Masakazu Hirota

Shintaro Yamaguchi

Wakana Tanaka

The University of Tokyo

Shohei Nosaki

University of Tsukuba

Kazuya Matsuo

Akari Fujimoto

Hitoshi Miyakawa

Utsunomiya University

Tsuyoshi Terakawa

Kyoto University

Kenichi Watanabe

Jumpei Taguchi

The University of Tokyo

Akiko Kanehara

Kazuki Ide

Keiichiro Suzuki

Osaka University

Takayuki Kuraishi

Kanazawa University

Yukiko Kimura

National Institutes of Natural Sciences

Tomomi Koshiyama

Ritsumeikan University

Yoshiaki Abe

University of Tsukuba

Azusa Kondoh

Pharmacy Biology & Life sciences

Katsuyoshi Takaoka

Taro Fuchikawa

Osaka City University

Akihiko Mougi

Shimane University

Kaori Sako

June-Sik Kim

RIKEN

Masafumi Kodama

Biology & Life sciences

Hiroyoshi Y. Tanaka

Okayama University

Hirohisa Ohno

Kyoto University

Kuniyasu Saitoh

Hidenori Nishio

Nagoya City University

Miu Tamamitsu

The University of Tokyo

Takuma Kokusho

Hiroshi Miyanishi

University of Miyazaki

Seiji Takashima

Shinshu University

Yasuo Oguri

Biology & Life sciences Life Science

Shintaro Munemasa

Okayama University

Yosuke Togashi

Medicine Biology & Life sciences

Tomoko Okamoto

Ryusuke Hatae

Kyushu University

Chie Aoki-Utsubo

Kobe University

Kenji Osabe

Tokyo Institute of Technology

Takashi Fukaya

The University of Tokyo

Chihiro Maeda

Material Science

Ayaka Ito

Taichi Noda

The University of Tokyo

Masashi Kanayama

Tokyo Medical and Dental University

Kenichi Kimura

University of Tokyo

Takeshi Kawabe

Medicine Biology & Life sciences

Kozue Shiomi

Biology & Life sciences

Satoshi Miura

Information Science

Toshiro Moroishi

Koji Atarashi

Ayako Gotoh

Konan University

Masaki Uchida

Mizuki Watanabe

Hokkaido University

Kunio Kondoh

Masayuki Morita

Ehime University

Nami Minato

Yuki Honda

Material Science

Akihiro Goto

Life Science Biology & Life sciences

Tetsuya Kadonosono

Tokyo Institute of Technology

Yoshihiro Ujihara

Nagoya Institute of Technology

Yuji Sakai

Tokushima University

Takuya Motooka

Aiko Sada

Okayama University

Masahiro Morimoto

Akihiro Nishiguchi

National Institute for Materials Science

Atsushi Fujimura

Okayama University

Taichi Itoh

Biology & Life sciences

Kotaro Mizuta

Kyoto University

Michihito Kono

Mizuki Endo

Susumu Jitsuki

Biology & Life sciences Life Science

Tomonori Matsumoto

Biology & Life sciences Medicine

Yuichiro Mishima

Kyoto Sangyo University