Miyako Shiraishi

Graduate School of Engineering Science, Osaka UniversityAssistant Professor*Profile is at the time of the award.

2019Inamori Research GrantsBiology & Life sciences

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Research topics: Elucidation of the cellular function of the ubiquitous protein, endonuclease V

Keyword

Summary: Endonuclease V is a ubiquitous protein conserved from E. coli to humans. This protein was first discovered as an endonuclease which is specific to hypoxanthine-containing DNA in 1994. Following this discovery, this protein was thought to have been a DNA repair protein: however, a novel role of endonuclease V in RNA editing was found in humans in 2013. In the present study, by revisiting the cellular role of endonuclease V in the hyperthermophilic archaeon Pyrococcus furiosus, I will seek to reveal the evolutionarily important role of endonuclease V.

Message from recipient

I am very grateful to the Inamori Fundation for giving me the opportunity to pursue my research. My hope is that the research supported by this grant would contribute to a better understanding of nature and I hope this will contribute to society someday.

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