Shohei Nosaki

Assistant Professor, Institutes of Life and Environmental Sciences, University of Tsukuba*Profile is at the time of the award.

2024Inamori Research GrantsBiology & Life sciences

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Research topics: Elucidation of molecular function and biological significance of the arginine-rich DNA-binding protein

Keyword

Summary: Although it has been revealed that protein liquid-liquid phase separation, which has attracted attention in recent years, is driven by intrinsically disordered regions, it is unclear whether domains with specific three-dimensional structures are involved in the liquid-liquid phase separation. Under these circumstances, I discovered that an arginine-rich DNA-binding protein, which is highly conserved in plants, forms droplets and gels in vitro, and also found a mutant that does not form droplets or gel. In this study, I will explore the molecular function and biological significance of the arginine-rich DNA-binding protein by making full use of biochemical and molecular biological analyzes using the mutant.

Message

It is an honor to receive research funding from your foundation, and I feel very motivated. I hope to elucidate new aspects of mechanism of signal transduction in plants from my own perspective and contribute to the development of science.

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