Shun Omagari

Assistant Professor, School of Materials and Chemical Technology, Institute of Science Tokyo*Profile is at the time of the award.

2025Inamori Research GrantsScience & Engineering

Research topics
Proof-of-concept of Novel Nanothermometry Technique based on Combination of Super-resolution Fluorescent Microscopy and Temperature-sensitive Luminescent Lanthanide Nano-beads
Keyword
Summary
The temperature of materials, devices, and biological systems is crucial information for device fabrication and operation, as well as for evaluating the physical properties of materials and biological systems and elucidating their underlying mechanisms. In recent years, with the advancement of nanotechnology, it has become increasingly important to analyze phenomena at the microscale, leading to growing interest in nanoscale temperature measurement techniques. This study aims to develop a novel nanoscale temperature measurement method with high spatial resolution and demonstrate its feasibility. Specifically, it combines RESOLFT, a type of super-resolution fluorescence microscopy, with lanthanide complexes that exhibit useful luminescent properties for temperature measurement.

Comment

The concept of nanoscale temperature measurement using phosphors has existed, but its realization has been challenging. This is because luminescent materials suitable for temperature measurement are poorly compatible with super-resolution fluorescence microscopy, which has spatial resolution beyond the diffraction limit of light. In this study, we propose a novel approach that sets itself apart from conventional temperature measurement techniques. By combining RESOLFT, a type of super-resolution fluorescence microscopy, with lanthanide complexes that exhibit favorable luminescent properties for temperature measurement, we aim to establish a technology that enables the precise visualization of temperature distribution at the true nanoscale. We are committed to advancing this research, expecting that this innovative approach will lead to a breakthrough in measurement technologies within the field of nanotechnology.

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