Shunsuke Tagami

Center for Biosystems Dynamics Research, RIKENUnit Leader*Profile is at the time of the award.

2019Inamori Research GrantsBiology & Life sciences

website

Research topics: Structural analysis and engineering of the biosynthesis system for “lasso” peptides

Keyword

Summary: Some bacteria are known to produce lasso peptides with a characteristic knot structure. It is reported that bacteria use lasso peptides to attack other bacteria, and thus application of this phenomenon to the development of pharmaceutical products is anticipated. This proposed research is intended to reveal how lasso peptides’ knot structure is formed by way of X-ray crystal structural analysis of the lasso peptide synthesis enzymes.

Message from recipient

I feel truly honored to be able to pursue my research with the grant from the Inamori Foundation. My hope is to contribute to the progress of humankind by making in-depth research into the basics.

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