Yosuke Togashi

Professor, Graduate School of Medicine，Dentistry and Pharmaceutical Sciences, Okayama University *Profile is at the time of the award.

2022Inamori Research GrantsBiology & Life sciences

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Research topics: Antitumor immunity and abnormal mitochondria in the tumor microenvironment

Keyword

Summary: In recent years, cancer immunotherapy has been used in clinical settings. In some cases, durable response can be achieved and the drug can be discontinued, like "cure". However, some patients do not respond, and the essence of cancer immunology needs to be clarified. In my previous study, I have found that mitochondria, organelles in cells involved in metabolism, may influence the activation of T cells. Therefore, in this study, I would like to analyze the effects on cancer immunotherapy in more detail to elucidate the essence of cancer immunology and to develop new cancer immunotherapies.

Message

Cells with mitochondrial abnormalities grow slowly and are very difficult to grow, but the results are very impressive. I hope that this research will benefit many patients with diseases.

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