Kazuhiko Yamamuro

Assistant Professor, Faculty of Medicine, Nara Medical University *Profile is at the time of the award.

2021Inamori Research GrantsBiology & Life sciences

Research topics: Identification of neural basis of fear memory formed by prefrontal cortex - paraventricular nucleus of thalamus circuit

Keyword

Summary: Adverse childhood experience is known to be accompanied by the onset or manifestation of time-slip phenomenon (fear memory), which causes confusion as if a painful experience in the past had occurred in the present, but there is no established treatment for it.　It is known that not only the prefrontal cortex and amygdala but also the paraventricular nucleus of the thalamus are involved in fear memory, but the details are not clear. Based on the fact that the paraventricular nucleus of the thalamus receives projections from oxytocin neurons and oxytocin is involved in fear memory, we would like to examine the onset or manifestation mechanism and treatment of fear memory in mice.

Comment

I am very grateful to have been selected for this prestigious research grant. I will do my best to meet the expectations of those who have selected me and the Inamori Foundation.

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